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Merck, Ridgeback’s Molnupiravir Could Be First Oral Antiviral Pill for COVID

Reduced risk of hospitalization or death by 50 percent in patients with mild-to-moderate COVID-19, based on positive interim analysis of Phase 3 study.

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By: Kristin Brooks

Managing Editor, Contract Pharma

Merck and Ridgeback Biotherapeutics announced that molnupiravir (MK-4482, EIDD-2801), an investigational oral antiviral medicine, significantly reduced the risk of hospitalization or death based on interim analysis of the Phase 3 MOVe-OUT trial in at risk, non-hospitalized adult patients with mild-to-moderate COVID-19.   At the interim analysis, molnupiravir reduced the risk of hospitalization or death by approximately 50%; 7.3% of patients who received molnupiravir were either hospitalized or...

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